The Atmo Gas Capsule is a world-first patented solution to accurately profile the gases within the gut, leading to better diagnosis and treatment of gastrointestinal disorders.

The gas-sensing capsule, when swallowed, can electronically report important data about the human gastrointestinal system by detecting gases in real-time from known locations within the gut and using these biomarkers for diagnosis, resulting in targeted treatment, earlier relief of symptoms and reduced healthcare costs.

The ingestible capsule offers a potential diagnostic tool for many disorders of the gut from IBS and IBD to carbohydrate malabsorption and intolerance.

Gut disorders are common and debilitating

Gut disorders are one of the most common ailments in the world affecting tens of millions of people.
These disorders include motility abnormalities, SIBO, IBS and IBD. Gases are important biomarkers of disease, dysfunction and dysbiosis.


20% of people suffer from gastrointestinal disorders in their lifetime.


30% of patients remain undiagnosed and suffer from the recurrence of disorders.


IBS affects 25 to 45 million people in the USA and 2 to 5 million in Australia.


GI disorders and disease treatment market (2013 USD).

Until now a method has not existed to measure GI gases in situ.

Current GI tools are limited

Unfortunately, current diagnostic methods for gastrointestinal disorders are often highly invasive or rely on subjective symptomatology and questionnaires.

Diagnostic methods such as aspiration, biopsy, endoscopy, motility pills, imaging pills and breath testing all have limitations.

Gas sensing in real-time from within the gut is an accurate, convenient method of diagnosing the common GI conditions affecting the millions of sufferers of food intolerances, motility disorders, SIBO and IBS.

“Any ability to monitor the production or consumption of chemicals in the environment of the gut is incredibly powerful.”

- Jack Gilbert, Microbiologist and Director of the Microbiome Center at the University of Chicago. Source: NPR

Introducing the Atmo Gas-Sensing Capsule

A safe and accurate way of measuring the concentration of various gases at the source of production in the gastrointestinal tract (GI tract) in real-time.

Atmo gas capsule in hand
A simple, non-invasive solution

The Atmo Gas Capsule allows tests to be performed at home, without impacting daily activities.

Step 1

Step 1

Patient attends physician’s office to discuss their condition.


Step 2

Patient swallows Gas Capsule with a standard meal.

Step 3

Step 3

Data is continuously transmitted from the Gas Capsule to the receiver, the phone app and the cloud.

Step 4

Step 4

Patient goes about their normal lifestyle and inputs symptoms and diet data in real time into the phone app.

Step 5

Step 5

Phone app notifies patient when disposable Gas Capsule has been expelled. No retrieval necessary.

Step 6

Step 6

Data is analysed and the physician discusses the results with the patient.


Within the Atmo Gas Capsule's 2cm-long polymer shell are gas sensors, a temperature sensor, a microcontroller, a radio-frequency transmitter, and button-sized silver-oxide batteries. The gas sensors are sealed within a special membrane that allows gas in but keeps out stomach acid and digestive juices.

The technology works by using sensors to measure different gases by adjusting their heating elements, and the data can then be transmitted to a mobile phone. Oxygen concentrations are used to track the capsule's progress throughout the GI tract.

Data is transmitted in real-time to a small receiver that can be carried in a pocket or left on the nightstand when someone is home. The receiver in turn transmits the data via Bluetooth to a cell phone, which can post the data online for easy monitoring by users and doctors.


Tracks location and evaluates constituents (%) of H₂, O₂, CO₂, CH₄ gas present as the capsule travels through the GI tract.

Will soon measure H₂S and short-chain fatty acids

Uses O₂ to track location

Temp sensor tells patient via phone app when capsule has exited

Data to receiver to phone to cloud

Data sent every 5 minutes for 72 hours

Big data delivers a normative data set

The Atmo Gas Capsule is a connected product ecosystem that can collect and aggregate patient data leading to a highly valuable normative data set of gas profiles.

Big Data diagram
Gas capsule trial at RMIT
Human clinical trials

Phase 1 human clinical trials have been successfully completed on 23 people.


Clinical trials of the Atmo Gas Capsule were conducted on 23 healthy participants adhering to either a low- or high-fibre diet. Results showed that the capsule is safe and reliable, and accurately shows the onset of food fermentation, highlighting their potential to clinically monitor digestion and normal gut health. The trials also demonstrated that the Atmo Gas Capsule could offer a much more effective way of measuring microbiome activities in the stomach, a critical way of determining gut health.

Gas concentrations in the gut are 5,000 to 10,000 times higher than those in the breath, which results in the Capsule’s superior signal to noise ratio when compared to breath testing.

The current method for measuring gas biomarkers is using breath tests. Breath tests, however, are an indirect measurement technique requiring the gases that are generated in the gut to be absorbed into the blood stream, circulated around the body, transferred into the lungs and finally exhaled out of the mouth. For this reason breath tests show low specificity and sensitivity when compared to the direct method used by the Atmo Gas Capsule.

Breath Test Comparison Chart TXH 04-01
Key benefits

The Atmo Biosciences Gas Capsule has a unique set of benefits that could revolutionise the way gut disorders and diseases are diagnosed and managed.

direct sensing

Direct sensing

At the source of gas production within the gut


Greater accuracy

Up to 10,000 times better than current standards



Patient data can be aggregated for clinical analysis and predictive algorithms

Low cost

Cheaper than all current methods

non invasive


Patients go about their normal life



The size of a common vitamin pill

location based monitoring

Real-time data collection

Data transmitted wirelessly to receiver, phone app and cloud in real-time from known location in the gut

future opportunities

Future opportunities

Potential applications span malabsorption to IBD


The Atmo Gas Capsule was invented at RMIT University in Melbourne, Australia, under the leadership of Professor Kourosh Kalantar-zadeh, together with Mr Nam Ha, Dr Kyle Berean, Dr Adam Chrimes and Dr Jian Zhen Ou, and is the result of eight years of research and development.

In 2018, Atmo Biosciences signed a licencing deal with RMIT securing the exclusive worldwide rights to commercialize the capsule. The capsule inventors are continuing to lead research and development at Atmo, in partnership with Planet Innovation.

Scientific publications

K. J. Berean, N. Ha, J. Z. Ou, A. F. Chrimes, D. Grando, C. K. Yao, J. G. Muir, S. A. Ward, R. E. Burgell, P. R. Gibson, K. Kalantar-zadeh, "The safety and sensitivity of a telemetric capsule to monitor gastrointestinal hydrogen production in-vivo in healthy subjects: a pilot trial comparison to concurrent breath analysis," Alimentary Pharmacology and Therapeutics. doi:10.1111/apt.14923

K. Kalantar-zadeh, K. J. Berean, N. Ha, A. F. Chrimes, K. Xu, D. Grando, J. Z. Ou, N. Pillai, J. L. Campbell, R. Brkljača, K. M. Taylor, R. E. Burgell, C. K. Yao, S. A. Ward, C. S. McSweeney, J. G. Muir, and P. R. Gibson, "A human pilot trial of ingestible electronic capsules capable of sensing different gases in the gut," Nature Electronics, vol. 1, no. 1, pp. 79-87, 2018/01/01 2018.

J. Z. Ou, J. J. Cottrell, N. Ha, N. Pillai, C. K. Yao, K. J. Berean, S. A. Ward, D. Grando, J. G. Muir, C. J. Harrison, U. Wijesiriwardana, F. R. Dunshea, P. R. Gibson, and K. Kalantar-zadeh, "Potential of in vivo real-time gastric gas profiling: A pilot evaluation of heat-stress and modulating dietary cinnamon effect in an animal model," Scientific Reports, Article vol. 6, 2016, Art. no. 33387.

K. Kalantar-zadeh, N. Ha, J. Z. Ou, and K. J. Berean, "Ingestible Sensors," ACS Sensors, Review vol. 2, no. 4, pp. 468-483, 2017.

K. Kalantar-zadeh, C. K. Yao, K. J. Berean, N. Ha, J. Z. Ou, S. A. Ward, N. Pillai, J. Hill, J. J. Cottrell, F. R. Dunshea, C. McSweeney, J. G. Muir, and P. R. Gibson, "Intestinal Gas Capsules: A Proof-of-Concept Demonstration," Gastroenterology, Article vol. 150, no. 1, pp. 37-39, 2016.

J. Z. Ou, C. K. Yao, A. Rotbart, J. G. Muir, P. R. Gibson, and K. Kalantar-zadeh, "Human intestinal gas measurement systems: in vitro fermentation and gas capsules," Trends in Biotechnology, vol. 33, no. 4, pp. 208-213, 2015/04/01/ 2015.

K. J. Berean, E. M. Adetutu, J. Z. Ou, M. Nour, E. P. Nguyen, D. Paull, J. McLeod, R. Ramanathan, V. Bansal, K. Latham, G. J. Bishop-Hurley, C. McSweeney, A. S. Ball, and K. Kalantar-zadeh, "A unique in vivo approach for investigating antimicrobial materials utilizing fistulated animals," Scientific Reports, Article vol. 5, 2015, Art. no. 11515.

Malcolm Hebblewhite

Malcolm Hebblewhite


Nick Peace

Nick Peace

Chairman of the Board

Chris Roberts

Dr. Chris Roberts AO

Non-Executive Director

Eduardo Vom

Eduardo Vom

Non-Executive Director

Dr Kyle Berean

Dr. Kyle Berean

VP Technology

James John

Dr. James John

VP Operations

Adam Chrimes

Dr. Adam Chrimes

Principal Engineer

Prof Kourosh Kalantar zadeh

Professor Kourosh Kalantar-zadeh

Lead Scientific Advisor

Prof Peter Gibson

Professor Peter Gibson

Lead Medical Advisor

Dr Jian Zhen Ou

Dr. Jian Zhen Ou

Scientific Advisor

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